BOC-D-PHE(4-CF 3)-(C*CH2)OH

BOC-D-PHE(4-CF 3)-(C*CH2)OH - Names and Identifiers

Name	Boc-(R)-3-Amino-4-(4-trifluoromethyl-phenyl)-butyric acid
Synonyms	RARECHEM AK PT B024 BOC-D-BETA-HOPHE(4-CF3)-OH BOC-D-PHE(4-CF 3)-(C*CH2)OH (R)-BOC-4-(TRIFLUOROMETHYL)-BETA-HOMOPHE-OH BOC-4-(TRIFLUOROMETHYL)-D-BETA-HOMOPHENYLALANINE BOC-(R)-3-AMINO-4-(4-TRIFLUOROMETHYLPHENYL)BUTANOIC ACID Boc-(R)-3-Amino-4-(4-trifluoromethyl-phenyl)-butyric acid BOC-(R)-3-AMINO-4-(4-TRIFLUOROMETHYL-PHENYL)-BUTYRIC ACID N-BETA-T-BUTOXYCARBONYL-D-HOMO(4-TRIFLUOROMETHYLPHENYL)ALANINE
CAS	269726-77-4

BOC-D-PHE(4-CF 3)-(C*CH2)OH - Physico-chemical Properties

Molecular Formula	C16H20F3NO4
Molar Mass	347.33
Density	1.246
Boling Point	449.7±45.0 °C(Predicted)
pKa	4.38±0.10(Predicted)
Storage Condition	2-8°C

BOC-D-PHE(4-CF 3)-(C*CH2)OH - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
FLUKA BRAND F CODES	10
Hazard Class	IRRITANT

BOC-D-PHE(4-CF 3)-(C*CH2)OH - Introduction

Boc-(R)-3-Amino-4-(4-trifluoromethyl-phenyl)-butyric acid is an organic compound with the following properties:

1. Appearance: white crystalline solid
2. molecular formula: C15H19F3NO4
3. Molecular weight: 337.32g/mol
4. Melting point: 70-73°C
5. Solubility: Soluble in some organic solvents such as dimethylformamide and dichloromethane

The main use of Boc-(R)-3-Amino-4-(4-trifluoromethyl-phenyl)-butyric acid is as a raw material in organic synthesis. It can be used to synthesize biologically active compounds, such as drug molecules in the field of medicine. Because its structure contains amino acids, it can also be used as an intermediate for the synthesis of polypeptide drugs.

Its preparation method can be achieved through the following steps:
1.3-amino -4-(4-trifluoromethylphenyl) butyric acid reacts with Boc protecting group to form Boc-(R)-3-Amino-4-(4-trifluoromethyl-phenyl)-butyric acid through electrophilic substitution under alkaline conditions. The electrophilic reagent used in this step may be Boc-imino, Boc-amidine reagent, or the like.
2. According to needs, subsequent purification and crystallization steps can be carried out according to the specific conditions of the reaction to obtain a pure product.

Regarding safety information, due to different experimental conditions and operating methods, please ensure that personal protective equipment such as laboratory gloves, protective glasses and laboratory coats are used correctly when conducting any chemical experiments or preparing compounds. In addition, the proper storage and handling of chemicals, comply with the relevant safety procedures, such as to avoid contact with skin and eyes, away from fire sources. If necessary, a chemist or safety specialist should be consulted for more detailed safety information.

Last Update：2024-04-09 21:04:16